Shenmeng Gao Selected Research

degrasyn

1/2020	WT1 facilitates the self-renewal of leukemia-initiating cells through the upregulation of BCL2L2: WT1-BCL2L2 axis as a new acute myeloid leukemia therapy target.
1/2020	Deubiquitinase inhibitor degrasyn suppresses metastasis by targeting USP5-WT1-E-cadherin signalling pathway in pancreatic ductal adenocarcinoma.

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Shenmeng Gao Research Topics

Disease

10	Neoplasms (Cancer) 10/2020 - 07/2011
9	Leukemia 01/2021 - 08/2016
7	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 11/2015
3	Neoplasm Metastasis (Metastasis) 01/2020 - 11/2016
3	Liver Cirrhosis (Hepatic Cirrhosis) 02/2014 - 07/2013
1	Hematologic Neoplasms (Hematological Malignancy) 01/2022
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2022
1	Multiple Myeloma 01/2021
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2021
1	Pathologic Processes 10/2020
1	Adenocarcinoma 01/2020
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Congenital Hypodysfibrinogenemia 08/2018
1	Lung Neoplasms (Lung Cancer) 11/2016
1	Sepsis (Septicemia) 01/2016
1	Carcinogenesis 11/2015
1	Hyperplasia 01/2015
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2015
1	Fibrosis (Cirrhosis) 02/2014
1	Lymphoma (Lymphomas) 07/2011

Drug/Important Bio-Agent (IBA)

5	MicroRNAs (MicroRNA)IBA 01/2018 - 07/2013
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2015
2	degrasynIBA 01/2020 - 01/2020
2	Long Noncoding RNAIBA 01/2019 - 11/2018
2	honokiolIBA 03/2017 - 11/2015
1	venetoclaxIBA 01/2022
1	Bortezomib (Velcade)FDA Link 01/2021
1	TetraspaninsIBA 10/2020
1	Membrane Proteins (Integral Membrane Proteins)IBA 10/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	WT1 ProteinsIBA 01/2020
1	Deubiquitinating EnzymesIBA 01/2020
1	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 01/2019
1	methoxypolyethyleneglycol- poly(lactic- co- glycolic acid)IBA 01/2019
1	Glycogen Synthase KinasesIBA 01/2019
1	Fibrinogen (Factor I)FDA Link 08/2018
1	Caspase 3 (Caspase-3)IBA 01/2018
1	Trypan Blue FDA Link 01/2018
1	Mebendazole (Anti-Worm)FDA Link 01/2018
1	UbiquitinIBA 03/2017
1	gamma-Glutamyl Hydrolase (Carboxypeptidase G2)IBA 03/2017
1	Oncogene Proteins (Oncogene Protein)IBA 03/2017
1	DNA (Deoxyribonucleic Acid)IBA 11/2016
1	Sincalide FDA Link 11/2016
1	Biological ProductsIBA 11/2016
1	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2016
1	Biomarkers (Surrogate Marker)IBA 08/2016
1	carbapenemaseIBA 01/2016
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 11/2015
1	Tissue Inhibitor of MetalloproteinasesIBA 02/2014
1	CollagenIBA 02/2014
1	TensinsIBA 01/2014
1	CurcuminIBA 01/2014
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2014
1	Chimeric Antigen ReceptorsIBA 07/2011
1	p38 Mitogen-Activated Protein KinasesIBA 07/2011

Therapy/Procedure

3	Therapeutics 01/2020 - 07/2011
2	Drug Therapy (Chemotherapy) 01/2018 - 08/2016
1	Heterologous Transplantation (Xenotransplantation) 01/2020